Regulatory mechanism of osteoclastogenesis by Wnt signaling
نویسندگان
چکیده
منابع مشابه
Regulatory mechanism of osteoclastogenesis by RANKL and Wnt signals.
Osteoclasts develop from monocyte-macrophage lineage cells under the regulation of osteoblasts. Osteoblasts express two cytokines essential for osteoclastogenesis, macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor-KappaB ligand (RANKL). Osteoblasts also produce osteoprotegerin (OPG), a decoy receptor for RANKL, which inhibits the interaction between RANKL and...
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ژورنال
عنوان ژورنال: Inflammation and Regeneration
سال: 2011
ISSN: 1880-9693,1880-8190
DOI: 10.2492/inflammregen.31.413